|The most frequent medical causes of issues with erections include high blood pressure and cholesterol. High cholesterol levels can cause problems below the trouser line since it may reduce blood flow to the male organs and other body parts. The high blood pressure is a health issue that could affect your sexual life the most. The penis's muscle is unable to relax, which means that there isn't enough blood flowing into the penis in order to make an erection. The restricted blood flow to the penis may be a result of antidepressant medications. Stress is also a significant factor and is often blamed for issues with erectile function and insufficient sexual performance.